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Earlier Detection of a Malignancy in Neurofibromatosis Type 1

Read more: "Earlier detection of a malignancy in neurofibromatosis type 1 (NF1)."

… at greater risk of developing a rare, aggressive form of cancer. Diagnosing malignant peripheral nerve sheath tumors (MPNSTs) often comes too late, after the cancer has spread and is difficult to treat. But an … the NFRI at Boston Children’s, published their findings in Cancer Discovery on Jan. 4, 2023.  The team collected 95 …
Physician
Karen Wright, MD, MS

Karen Wright, MD, MS

Attending, Dana-Farber/Boston Children's Cancer and Blood Disorders Center
Assistant Professor of Pediatrics, Harvard Medical School

The diagnosis of cancer is incredibly difficult for anyone, but when it’s your child, it’s particularly devastating. I make sure to reassure patients, parents, families and caregivers that this is...

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Publications

… ahead of print] Tissue factor expressed by circulating cancer cell-derived microparticles drastically increases the … (2014) NETosis: a new factor in tumor progression and cancer-associated thrombosis. Demers M, Wagner DD Semin … [PubMed] Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for …
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… work in the use of stem cell biology to study lung cancer and lung disease. Pediatric high-grade gliomas: … Children’s Hospital, Co-Leader for the Dana-Farber/Harvard Cancer Center Leukemia Program, and a Professor of … study from Boston Children’s. Dana-Farber/Boston Children’s Cancer and Blood Disorders Center recognized for exceptional …
Physician
Eva Guinan, MD

Eva Guinan, MD

Director of Translational Research, Department of Radiation Oncology
Associate Professor of Radiation Oncology, Harvard Medical School