After residency, Dr. Wren worked in several different aspects of inpatient and outpatient Pediatrics before settling on Pediatric Emergency Medicine at Salem Hospital, where she worked for 18 years, including 7 years in a leadership role. She then spent 4.5 years as a Newborn Hospitalist at Mt. Auburn Hospital before working 3 years at PM Pediatrics, a pediatric urgent care. She joined PHCA in October of 2022 where she sees children for sick and urgent care visits.